Skripsi

Profil Demografi dan Klinis Pasien Meningioma Intrakranial di RSUPN Dr. Cipto Mangunkusumo Tahun 2020 –2024 = Demographic and Clinical Profile of Intracranial Meningioma Patient in RSUPN Dr. Cipto Mangunkusumo during 2020–2024.

Latar Belakang Meningioma merupakan tumor otak jinak intrakranial yang paling sering ditemukan. Meskipun tumbuh lambat, meningioma tetap dapat memengaruhi kualitas hidup pasien. Temuan demografis dan klinis pasien meningioma masih bervariasi antarstudi di Indonesia. Oleh karena itu, penelitian ini bertujuan untuk memberikan gambaran terkait profil pasien meningioma intrakranial di RSUPN Dr. Cipto Mangunkusumo sebagai pusat rujukan nasional. Metode Penelitian bersifat observasional deskriptif potong lintang dilakukan menggunakan data sekunder berupa registri dan rekam medis elektronik. Data yang diambil mencakup jumlah kasus, jenis kelamin, usia, lokasi tumor, gambaran klinis, jenis operasi, dan tingkat reseksi tumor. Analisis dilakukan secara univariat dan bivariat deskriptif. Hasil Ditemukan 519 kasus meningioma intrakranial dengan rasio perempuan terhadap lakilaki sebesar 11,65:1. Median usia saat diagnosis adalah 46 (19–82) tahun, dengan sebaran tertinggi pada kelompok 41-50 tahun (47,6%). Lokasi tumor paling sering ditemukan pada sphenoorbita (26,4%), multipel (13,2%), dan tuberculum sella (10,4%). Nyeri kepala (73,9%), gangguan penglihatan (67,3%), dan proptosis (36,8%) merupakan gambaran klinis yang paling banyak dilaporkan. Sebagian besar pasien menjalani operasi dengan pendekatan kraniotomi (62,9%). Subtotal resection (70,1%) merupakan tingkat reseksi terbanyak yang dilakukan. Kesimpulan Profil pasien meningioma intrakranial dalam penelitian ini didominasi oleh perempuan dan usia dewasa tengah, dengan sebagian besar tumor berada di skull base. Gambaran klinis, jenis operasi, dan tingkat reseksi tumor berhubungan dengan lokasi tumor. Temuan tersebut menegaskan pentingnya kewaspadaan klinis terhadap gejala nonspesifik serta perlunya optimalisasi penatalaksanaan komprehensif pada rumah sakit rujukan nasional.
Kata Kunci: kraniotomi, meningioma, nyeri kepala, profil, sphenoorbita, tumor otak


Introduction Meningioma is the most common benign intracranial brain tumor. Despite its typically slow growth, it can substantially affect patients’ quality of life. Demographic and clinical profiles of meningioma in Indonesia remain inconsistent across studies. This study aims to describe the profile of intracranial meningioma patients treated at Dr. Cipto Mangunkusumo National General Hospital, a national referral center. Method A descriptive cross-sectional study was conducted using secondary data from the institutional brain tumor registry and electronic medical records. Variables included case frequency, sex, age, tumor location, clinical manifestations, surgical approach, and extent of resection. Data were analyzed using univariate and descriptive bivariate methods. Results A total of 519 intracranial meningioma cases were identified, with a female-to-male ratio of 11.65:1. The median age at diagnosis was 46 years (range 19–82), with the highest distribution in the 41–50-year group (47.6%). The most frequent tumor sites were sphenoorbita (26.4%), multiple (13.2%), and tuberculum sella (10.4%). Headache (73.9%), visual impairment (67.3%), and proptosis (36.8%) were the predominant clinical manifestations. Most patients underwent craniotomy (62.9%), and subtotal resection (70.1%) was the most common extent of resection performed. Conclusion Intracranial meningioma in this study predominantly affected women and middle-aged group, with most cases located at the skull base. Clinical presentation, surgical approach, and extent of resection were closely related to tumor location. These findings highlight a distinctive pattern of meningioma presentation in a national referral setting and underscore the importance of clinical vigilance and comprehensive management strategies.
Keywords: brain tumor, craniotomy, headache, meningioma, profile, sphenoorbita