Tesis

Korelasi Antara Kadar Magnesium Serum dan Kekuatan Genggam Tangan pada Pasien Malnutrisi di Rumah Sakit Cipto Mangunkusumo = Correlation Between Serum Magnesium Levels and Handgrip Strength in Malnourished Patients at Cipto Mangunkusumo Hospital.

Latar Belakang: Magnesium (Mg) berperan penting pada metabolisme dan fungsi otot serta sering ditemukan defisiensi pada malnutrisi. Defisiensi magnesium dihubungkan dengan penurunan kekuatan otot dan kapasitas fungsional pada pasien malnutrisi. Kekuatan genggam tangan (KGT) adalah alat ukur sederhana untuk menggambarkan kekuatan otot pada pasien malnutrisi. Korelasi antara kadar Mg serum dengan KGT pada pasien malnutrisi dewasa belum banyak diteliti. Penelitian ini bertujuan untuk mengetahui korelasi antara kadar Mg serum dengan KGT pada pasien malnutrisi dewasa di RSCM. Metode: Penelitian ini menggunakan disain potong lintang pada 42 pasien malnutrisi dewasa usia 18-59 tahun di pelayanan rawat jalan RSCM. Pengumpulan data dilakukan dengan pemeriksaan KGT menggunakan hand dynamometer Camry®, kadar magnesium serum, wawancara asupan melalui food recall, asupan Mg dengan SQ-FFQ, aktivitas fisik dengan kuesioner IPAQ, dan skrining sarkopenia dengan SARC-F. Hasil: Nilai median usia subjek 33 tahun (18–58 tahun), proporsi sama antara lakilaki dan perempuan, rentang IMT dengan median 17,6 (16,0–18,4) kg/m2, rerata kadar Mg serum 1,95 ± 0,22 mg/dL, dan nilai KGT 22,7 ± 7,2 kg. Dilakukan uji korelasi antara kadar Mg serum dengan KGT. Tidak ditemukan adanya korelasi bermakna antara kadar Mg serum dengan nilai KGT (r = 0,107, p = 0,502). Beberapa faktor lain yang belum diperiksa pada penelitian ini seperti besar massa otot, kadar vitamin D dan kalsium serum, serta jumlah sampel dapat mempengaruhi hasil ini. Kesimpulan: Tidak terdapat korelasi antara kadar Mg serum dengan KGT pada pasien malnutrisi dewasa rawat jalan RSCM.
Kata Kunci: kadar magnesium serum, kekuatan genggam tangan, malnutrisi, pasien dewasa.


Background: Magnesium (Mg) plays a vital role in muscle metabolism and function and is frequently deficient in malnourished individuals. Magnesium deficiency has been associated with decreased muscle strength and functional capacity in malnourished patients. Handgrip strength (HGS) is a simple and practical tool to assess muscle strength in these patients. However, to date few studies have examined correlation between serum Mg levels and HGS in malnourished adults. This study aimed to investigate the correlation between serum magnesium levels and handgrip strength in adult malnourished patients at Cipto Mangunkusumo Hospital (RSCM) outpatient clinics. Methods: This cross-sectional study included 42 adult malnourished patients aged 18–59 years visiting the outpatient clinics at RSCM. Data were collected through measurements of handgrip strength using a Camry® hand dynamometer, serum magnesium levels, dietary intake through 24-hour food recall, magnesium intake using a semi-quantitative food frequency questionnaire (SQ-FFQ), physical activity using the IPAQ and sarcopenia screening with SARC-F questionnaires. Results: The median age of the subjects was 33 years (range: 18–58), with equal representation of males and females. The median BMI was 17.6 kg/m² (range: 16.0– 18.4). The mean serum magnesium level was 1.95, SD 0.22 mg/dL, and the mean handgrip strength was 22.7, SD 7.2 kg. Pearson correlation analysis showed no significant association between serum magnesium levels and handgrip strength (r = 0.107, p = 0.502). Several unmeasured factors such as muscle mass, serum levels of vitamin D and calcium, and sample size may have influenced these findings. Conclusion: There was no significant correlation between serum magnesium levels and handgrip strength in adult malnourished patients at RSCM.
Keywords: serum magnesium levels, handgrip strength, malnutrition, adult patients.