Skripsi

Hubungan Komposisi Tubuh dengan Dislipidemia pada Pasien DMT2 di Puskesmas DKI Jakarta = The relationship between body composition and dyslipidemia in T2DM patients at community health centers in DKI Jakarta.

Latar Belakang Prevalensi diabetes tipe 2 (DMT2) terus meningkat dari setiap tahunnya, baik dalam skala global maupun nasional. DMT2 dapat memengaruhi abnormalitas metabolisme lipid, yaitu dislipidemia. Sebagian besar pasien DMT2 mengalami dislipidemia. Namun, dislipidemia juga dapat dipengaruhi oleh berbagai faktor lainnya, salah satunya komposisi tubuh. Sementara itu, penelitian mengenai hubungan komposisi tubuh (massa lemak, persentase massa lemak, lean body mass, dan lemak viseral) dengan dislipidemia pada pasien DMT2 masih terbatas sehingga peneliti ingin meneliti hubungan tersebut. Metode Studi observasional cross-sectional ini melibatkan 171 pasien dewasa dengan riwayat DMT2. Pengukuran BIA dan kadar profil lipid telah dilakukan pada penelitian utama. Data baseline dianalisis menggunakan uji perbedaan rerata untuk melihat hubungan komposisi tubuh terhadap dislipidemia. Selain itu, analisis juga menggunakan uji korelasi untuk melihat hubungan komposisi tubuh dengan setiap kadar profil lipid, yaitu kolesterol LDL, non-HDL, dan trigliserida. Hasil Tidak terdapat hubungan yang bermakna (p > 0,05) antara komposisi tubuh dengan dislipidemia atau setiap profil lipid. Kesimpulan Komposisi tubuh, berupa massa lemak, persentase massa lemak, lean body mass, dan lemak viseral, tidak memiliki hubungan yang bermakna dengan dislipidemia dan profil lipid (kolesterol LDL, kolesterol non-HDL, dan trigliserida) pada pasien DMT2.
Kata Kunci: dislipidemia, diabetes tipe 2, lemak viseral, massa lemak, massa otot, persentase massa lemak


Introduction The prevalence of type 2 diabetes (T2DM) continues to increase each year, both globally and nationally. T2DM can affect lipid metabolism abnormalities, namely dyslipidemia. The majority of T2DM patients experience dyslipidemia. However, dyslipidemia can also be influenced by various other factors, one of which is body composition. Meanwhile, research on the relationship between body composition (fat mass, fat mass percentage, lean body mass, and visceral fat) and dyslipidemia in T2DM patients is still limited, prompting the researcher to investigate this relationship. Method This cross-sectional observational study involved 171 adult patients with a history of T2DM. BIA measurements and lipid profile levels were conducted in the main study. Baseline data were analyzed using a mean difference test to assess the relationship between body composition and dyslipidemia. In addition, a correlation test was used to examine the relationship between body composition and each lipid profile level, including LDL cholesterol, non-HDL, and triglycerides. Results There was no significant relationship (p > 0.05) between body composition and dyslipidemia or any ofthe lipid profiles. Conclusion Body composition, including fat mass, fat mass percentage, lean body mass, and visceral fat, does not have a significant relationship with dyslipidemia and lipid profiles (LDL cholesterol, non-HDL cholesterol, and triglycerides) in T2DM patients.
Keywords: body fat percentage, dyslipidemia, fat mass, muscle mass, type 2 diabetes, visceral fat