Skripsi

The Association between Azoospermia Etiology and Sperm Retrieval Success Rates on Male Patient = Asosiasi antara Etiologi Azoospermia dan Tingkat Keberhasilan Pengambilan Sperma pada Pasien Pria.

Introduction Azoospermia, known as absence of sperm in ejaculation, is a major cause of male infertility, classified as pre-testicular, testicular, post-testicular. Pre-testicular and posttesticular causes allow for fertility intervention, while testicular causes are irreversible with lower success rates. Indonesia have a data scarcity to support doctors to determine the sperm retrieval success rate between different etiology. Doctors could be benefited by knowing the classifications of the causes for azoospermia and how it affects the sperm retrieval success rate. This study aimed to investigate the associaton between etiology of azoospermia and the success rate of sperm retrieval Method We conducted a cross-sectional analysis of data from hospitals in Jakarta. The data includes 659 azoospermia patient who have undergone sperm retrieval procedures. Azoospermia etiology was categorized into pre-testicular, testicular, and post-testicular azoospermia. Data who have two or more simultaneous etiology were considered as multi-factorial azoospermia. However, multi-factorial azoospermia is excluded from the analysis. Chi-square tests were used to analyse the association between etiology of azoospermia and sperm retrieval success rate. Sperm retrieval methods association with sperm retrieval success rate was also analyse with chi-square test. The ethical clearance is obtained for this research. Results The data consist of 111 pre-testicular azoospermia patients, 112 testicular azoospermia patients, 62 post-testicular azoospermia patients, and 374 multi-factorial azoospermia patients. Chi-square analysis revealed a significant association between azoospermia etiology and sperm retrieval success rate (χ2= 134.179, p =