Tesis

Uji validitas internal dan reliabilitas kuesioner epilepsi untuk menegakkan diagnosis epilepsi dan tipe kejang pada anak dengan kejang tanpa provokasi usia 1 bulan sampai dengan 18 tahun = Internal validity and reliability of the epilepsy questionnaire to establish the diagnosis of epilepsy and type of seizure in children aged 1 month to 18 years old with unprovoked seizures.

Latar belakang Angka misdiagnosis epilepsi pada anak masih cukup tinggi yakni sebesar 25-30%. Kuesioner merupakan instrumen untuk menegakkan diagnosis epilepsi pada anak dengan cara lebih mudah dan murah Tujuan Mengetahui validitas internal dan reliabilitas kuesioner untuk menegakkan diagnosis epilepsi dan tipe kejang pada anak usia 1 bulan-18 tahun dengan kejang tanpa provokasi Metode Uji potong lintang di bulan Maret-Juni 2023 pada anak usia 1 bulan-18 tahun dengan kejang tanpa provokasi interval lebih dari 24 jam. Pertanyaan kuesioner mencakup diagnosis epilepsi (tiga domain) dan tipe kejang. Uji validitas internal dan reliabilitas kuesioner mencakup face validity, validitas isi, validitas konkuren, validitas konvergen dan Cronbach’s alpha Hasil Terdapat 75 anak rerata usia 52,8 bulan, 44 laki-laki, 54 terdiagnosis epilepsi dan 26 berusia 1 - 6 tahun. Skor I-CVI, S-CVI dan CVR adalah 1. Nilai r hitung melebihi nilai r tabel (p < 0.001). Nilai AUC dan nilai potong domain 1, domain 2, domain 3 dan tipe kejang berturut-turut adalah 0,85, skor 6 ke atas, sensitivitas 92,5%, spesifisitas 75% (IK 95% = 0,685 s/d 1,00; p=0,001);0,93, skor 20, sensitivitas 95,3%, spesifisitas 90% (IK 95% =0,82 s/d 1,00; p=0,0001); 0,976, skor 2, sensitivitas 94,5%, spesifisitas 100% (IK 95% = 0,94 s/d 1,00; p=0,0001 ); 0,889, skor 5 ke atas, sensitivitas 72%, spesifisitas 97% (IK 95% = 0,783 s/d 0,995; p=0,0001). Cronbach’s alpha ketiga domain dan tipe kejang berturut-turut adalah 0,698; 0,785; 0,886; 0,806 Simpulan Kuesioner penegakkan diagnosis epilepsi dan tipe kejang pada anak usia 1 bulan-18 tahun memiliki validitas internal dan reliabilitas baik.
Kata kunci: epilepsi, diagnosis, kuesioner, validitas internal, reliabilitas


Background The misdiagnosis rate of epilepsy in children is quite high, at 25– 30%. The questionnaire can help to diagnose epilepsy in a more practical manner. Objective Evaluate the internal validity and reliability of the epilepsy questionnaire to establish the diagnosis of epilepsy and the type of seizure in children aged 1 month to 18 years Methods A cross-sectional study conducted during March–June 2023 in children with unprovoked seizures occurring more than once at intervals of more than 24 hours. The questions encompass the diagnosis of epilepsy (divided into three domains) and the type of seizure. Internal validity and reliability testing consist of face validity, content validity, concurrent validity, convergent validity, and Cronbach’s alpha. Results 75 children were included (mean age=52.8 months); 44 were boys, 54 were diagnosed with epilepsy, and 26 had an age range of 1 to 6 years. I-CVI, S-CVI, and CVR score was one. r value for each question exceeded the overall r value (p < 0.001). AUC value and cut-off score for each domain and type of seizure is 0.85, 6, sensitivity 92,5%, specificity 75% (95% CI=0.685-1.00, p=0.001); 0.93, 20, sensitivity 95,3%, specificity 90% (95% CI=0.82-1.00, p=0.0001); 0.976, 2, sensitivity 94.5%, specificity 100% (95% CI=0.94-1.00, p=0.0001); and 0.889, 5, sensitivity 72%, specificity 97% (95% CI 0.783-0.995, p=0.0001), respectively. Cronbach’s alpha for each domain and type of seizure is 0.698, 0.785, 0.886, and 0.806, respectively. Conclusion The questionnaire is internally valid and reliable to establish the diagnosis of epilepsy and type of seizure in children aged one month to 18 years.
Keywords: epilepsy, diagnosis, questionnaire, internal validity, reliability