Tesis

Korelasi Status Gizi Pascaprosedur Arterial Swtich Operation Pada Transposition Intact Ventricular Septum Usia ≥30 hari = Nutritional status correlation with Arterial switch outcome in Transposition with Intact Ventricular Septum age ≥30 days.

Latar belakang: Arterial Switch Operation (ASO) merupakan prosedur utama pada Transposition Intact Ventricular Septum (TGA-IVS). TGA-IVS kehadiran terlambat (usia ≥30 hari) mempengaruhi kesintasan pascaprosedur ASO dan umum ditemukan di negara berkembang, termasuk Indonesia. Semakin besar usia pada populasi penyakit jantung kongenital, terutama TGA-IVS, umumnya disertai status gizi kurang. Hubungan antara status gizi terhadap kesintasan pascaprosedur ASO pada TGA-IVS kehadiran terlambat belum diketahui Metodologi: Penelitian studi potong lintang berdasarkan data sekunder dari rekam medis pada pasien TGA-IVS≥ 30 hari yang menjalani operasi ASO periode 2015-2021.Variabel utama yang dinilai adalah status gizi berdasarkan kurva status gizi WHO 2006 Variabel yang ikut dinilai antara lain usia, jenis kelamin, anomali koroner, pola anomali, jenis ASO, lama penggunaan mesin jantung paru, dan penggunaan klem silang aorta terhadap mortalitas pascaprosedur ASO. Hasil: Terdapat 89 anak dengan kehadiran terlambat; 68,53% memiliki status gizi kurang/buruk. Karakteristik pasien TGA-IVS kehadiran terlambat adalah laki-laki (67,2- 67,9%), tidak memiliki anomali koroner dan memiliki pola anomali koroner normal (67,2-78,6%) dan menjalani ASO primer (67,9-68,9%). Status gizi kurang/buruk tidak memiliki hubungan terhadap risiko kemation pascaprosedur ASO (OR: 2,41, P:0,661) dibandingkan status gizi cukup. Lama mesin jantung paru merupakan prediktor mortalitas independen (p = 0,031) Simpulan: Status gizi rendah tidak memilki hubungan terhadap mortalitas pascaprosedur ASO pada TGA-IVS kehadiran terlambat.
Kata Kunci: Arterial Switch; Status gizi; Transposition of great arteries; mortalitas.


Background: Arterial Switch Operation (ASO) is the main procedure for Transposition of with Intact Ventricular Septum (TGA-IVS). Late presenter TGA-IVS (age ≥30 days) has lower postoperative ASO survival and commonly found in developing country, including Indonesia. Older age in congenital heart disease, including TGA-IVS, associated with poor nutritional status. The correlation between nutritional status and mortality post ASO in late presenter TGA-IVS remains unknown. Method: a cross sectional study based on secondary data based on medical record of late presenter TGA-IVS who undergoned ASO in 2015-202. The main measured variable is nutritional status based on WHO 2006 nutritional status curves. Other measured variables are age at intervention, gender, coronary anomaly, coronary patterns, ASO types, cardiopulmonary bypass time, aortic crosss-clamp time and hospital mortality post ASO Result: 89 children identified as late presenter TGA-IVS; 68,53% with poor nutritional status. The late presenter TGA-IVS characteristics are male (67,2-67,9%), normal coronary anatomy and pattern (67,2-78,6%), and mostly underwent primary ASO (67,9- 68,9%). Poor nutritional status has no correlation (OR: 2,41, P:0,661) with mortality outcome post ASO if compared with normal nutritional status. CPB time is an independent risk factor for mortality(p = 0,031). Conclusion: No correlation between poor nutritional status with mortality outcomes post ASO procedure in late presenter TGA-IVS
Keywords : Arterial Switch; nutritional status; Transposition of great arteries; mortality.