Skripsi

Hubungan Status Vaksinasi COVID-19 dengan Kualitas Hidup Tenaga Kesehatan Pasca Infeksi Akut COVID-19 (Long Covid) = Association between COVID-19 Vaccination Status and Quality of Life (QoL) among Healthcare Workers with Post-Acute COVID-19 Infection (Long Covid).

Latar belakang: Pandemi COVID-19 sudah memasuki fase akhirnya dengan tren penurunan kasus dan kematian yang terkonfirmasi. Akan tetapi, masih terdapatnya beban kesehatan berkepanjangan pada penyintas COVID-19 disebabkan oleh post-acute sequelae COVID-19 atau long covid. Long covid terjadi ketika ditemukannya gejala COVID-19 fase-akut persisten lebih dari 12 minggu sejak onset. Bermanifestasi secara multi-sistem, gejala long covid mempengaruhi aspek fisik, mental, dan sosial sehingga berdampak besar terhadap kualitas hidup. Vaksinasi selain sebagai bentuk pencegahan transmisi COVID-19 juga dilaporkan memberikan resolusi klinis long covid lebih baik. Hal ini cukup penting, terutama untuk tenaga kesehatan yang memiliki risiko kontak erat tinggi. Maka, studi ini bertujuan untuk mengetahui hubungan status vaksinasi dengan kualitas hidup tenaga kesehatan dengan long covid Metode: Penelitian ini dilakukan dengan pendekatan potong-lintang dengan mengolah data sekunder. Rekrutmen subjek dilakukan dalam jangka waktu Juni 2021 – Maret 2022 dengan kriteria inklusi berupa riwayat terinfeksi COVID-19, berprofesi tenaga kesehatan, dan teridentifikasi dengan satu gejala pasca-akut COVID. Subjek loss to follow-up dieksklusikan. Analisis data dilakukan secara deskriptif dan analitik dengan menggunakan uji chi-square dengan kemaknaan 95% (p 8.41. Analisis chi-square menghasilkan hubungan signifikan antara status vaksinasi dengan skor SGRQ dan kualitas hidup tenaga kesehatan dengan diagnosis long covid [PR 0.489 (0.312, 0.768), p=0.007)]. Selanjutnya, uji regresi logistik menghasilkan tidak adanya hubungan signifikan antara usia, jenis kelamin, IMT, komorbid, riwayat merokok, riwayat alkohol, frekuensi terinfeksi COVID-19, dan jumlah gejala fase akut dengan skor SGRQ. Kesimpulan: Terdapatnya hubungan signifikan antara status vaksinasi dengan kualitas hidup tenaga kesehatan dengan diagnosis long covid. Penelitian lanjutan direkomendasikan dengan sampel yang lebih besar dengan instrumen kualitas lain seperti EQ-5D-3L atau SF-36
Kata kunci: covid-19, kualitas hidup, long covid, tenaga kesehatan



Introduction: The COVID-19 pandemic is approaching its with an increasingly downfall trend of confirmed cases and mortalities. However, there still persists a continuous healthcare burden among COVID-19 survivors due to post-acute sequelae COVID-19 or long covid. Long covid occurs when symptoms from the acute-phase of COVID-19 lingers for more than 12 weeks since its onset. As a multi-system disease, symptoms tend to affect the physical, mental, and social aspect – and thus greatly impacting quality of life. Other than being a preventive method for COVID-19 transmission, vaccination has also been reported with better clinical resolution among long covid patients. This is detrimental, especially for healthcare workers who are at high risk of COVID-19 transmission. Hence, this study aims to analyze the association between vaccination and quality of life among healthcare workers. Methods: This study implemented a cross-sectional study design. Subjects were taken from a secondary data set which conducted recruitment within June 2021 – March 2022 with the following inclusion criteria: history of COVID-19 infection, a registered healthcare worker, and reported at-least one post-acute symptom. Subjects who were lost to follow-up are excluded. Statistical analyses were conducted descriptively and analytically using cross-tabulation (chi-square) with 95% significance (p 8.41. Chi-square analysis showed significant association between vaccination with SGRQ score and quality of life of healthcare workers [PR 0.489 (0.312, 0.768), p=0.007)]. Logistic regression analysis yielded no significant association between age, gender, BMI, comorbidities, smoking, alcohol. frequency of getting COVID-19, and number of acute-phase symptoms with SGRQ score Conclusion: Significant association between vaccination and quality of life of healthcare workers diagnosed with long covid was shown. Further research is recommended with a bigger sample size and additional quality of life measurement tools such as EQ-5D-3L and SF-36
Keywords: covid-19, healthcare workers, long covid, quality of life