Tesis

Efektivitas Filtrasi Respirator N95 Pasca-Paparan UVGI Berulang di Bilik UVGI RSUPN Dr. Cipto Mangunkusumo = Effectivity of N95 Respirators Filtration After Repeated UVGI Disinfection In UVGI Chamber of RSUPN Dr. Cipto Mangunkusumo.

Latar belakang: Pandemi Coronavirus disease 2019 (COVID-19) menyebabkan keterbatasan alat pelindung diri (APD) yang menjadi perhatian mendesak saat ini. Disinfeksi APD, terutama respirator N95 merupakan cara yang dilakukan untuk menanggulangi keterbatasan tersebut. Ultraviolet Germicidal Irradiation (UVGI) merupakan salah satu cara desinfeksi yang menjanjikan dan aman, sehingga respirator N95 dapat digunakan kembali. Bilik UVGI merupakan metode yang efektif dalam disinfeksi respirator N95 terhadap SARS-CoV-2,namun efek paparan UVGI dan pengaruhnya terhadap kemampuan filtrasi terhadap respirator N95 belum diketahui. Tujuan penelitian: Untuk mengevaluasi efektivitas filtrasi respirator N95 setelah paparan UV-C di Bilik UVGI untuk mengatasi kekurangan alat pelindung diri dengan menggunakan kembali respirator N95 sekali pakai. Metode: Penelitian ini adalah studi ekperimental dua kelompok paralel untuk melihat efek paparan UVGI berulang terhadap filtrasi 2 tipe respirator N95 2 (8210 dan 1860) menggunakan aerosol particle counter (CEM DT-9850M) setelah paparan UVGI berulang sebanyak 10 siklus di Bilik UVGI Departemen THT-KL RSCM. Objek penelitian berasal dari 2 kelompok respirator N95 sebanyak 25 buah tiap kelompok. Hasil: Hasil penelitian didapatkan tidak terdapat perbedaan bermakna pada respirator N95 pasca-paparan UVGI berulang hingga 10 siklus dengan rerata filtrasi pada 2 tipe respirator, serta tidak terdapat perubahan signifikan kemampuan filtrasi respirator N95 pasca-paparan UVGI berulang. Kesimpulan: Filtrasi respirator N95 pada penelitian ini dapat dipertahankan > 95% pasca-paparan UVGI berulang hingga dosis kumulatif 10.126˗16.200mJ/cm 2 di Bilik UVGI Departemen THT-KL RSCM
Kata kunci: Radiasi UV-C, bilik UVGI, desinfeksi, respirator N95, filtrasi


Background: Shortages of personal protective equipment (PPE) including N95 respirators are an urgent concern in the setting of the global COVID-19 pandemic. Disinfection of PPE could be useful to overcome this limitation. Ultraviolet Germicidal Irradiation (UVGI) is a promising and safe way of disinfection, so that the N95 respirator can be used again. The UVGI chamber is an effective method of disinfection of N95 respirators against SARS-CoV-2, however the effect of UVGI exposure and its effect on the filtration ability of N95 respirators is uncertain. Purpose: To evaluate the filtration effectivity of N95 respirators after UV-C in UVGI chamber to overcome the shortage of personal protective equipment by reusing disposable N95 respirators. Methods: This study is a parallel two-group experimental study to see the effect of repeated UVGI exposure on the filtration of 2 types of N95 respirators (8210 and 1860) using an aerosol particle counter (CEM DT-9850M) after 10 cycles of repeated UVGI exposure in the UVGI chamber of the ENT Department RSCM The object of the study came from 2 groups of N95 respirators, with 25 per group. Results: The results showed that there were no significant differences in the N95 respirator after repeated UVGI exposure for up to 10 cycles with the mean of filtration for 2 types of respirators, and there was no significant change in the filtration ability of the N95 respirator after repeated UVGI exposure. Conclusion: In this study, N95 respirator filtration was maintained > 95% after repeated UVGI exposure with cumulative dose of 10.126-16.200 mJ/cm 2 in UVGI chamber from Otolaryngology Head and Neck Surgey Department, RSCM.
Keyword: UV-C radiation, UVGI chamber, disinfection, N95 respirators, filtration