Tesis

Kesesuaian Hasil Ultrasonografi Elastografi Metode Strain Ratio dengan Metode 5-Point Color Scale Pada Tumor Payudara = Suitability of Elastographic Ultrasound Results between Strain Ratio and 5-Point Color Scale Method on Breast Tumors.

Terdapat beberapa metode ultrasonografi payudara teknik strain elastography, yang sering digunakan adalah metode 5-point color scale. Metode ini mengklasifikasi tumor payudara secara kualitatif yang relatif subyektif dengan variasi interobserver yang besar saat interpretasi. Sehingga perlu dilakukan uji kesesuaian metode 5-point color scale dengan metode yang lebih obyektif. Pemeriksaan ultrasonografi payudara teknik strain elastography metode 5-point color scale dan strain ratio menggunakan transduser linear 7-12 MHz pesawat ultrasonografi GE tipe Logic S8 dilakukan sendiri oleh peneliti, kemudian dikonfirmasi oleh dokter spesialis radiologi konsultan payudara sebelum pendataan. Kesesuaian hasil pemeriksaan metode 5-point color scale dan strain ratio, dianalisis menggunakan kurva ROC. Dari 28 sampel tumor payudara dari 14 subyek didapatkan, nilai rerata ± SD strain ratio adalah 6,5 ± 1,8 pada tumor dengan skor 4-5 (ganas) menggunakan metode 5-point color scale, sedangkan 2,9 ± 1,7 pada tumor dengan skor 1-3 (tidak ganas) menggunakan metode 5-point color scale (p 0,000). Nilai AUC pada kurva ROC adalah 0,93 ± 0,05 (p 0,000) untuk nilai strain ratio. Titik potong terbaik untuk nilai strain ratio adalah 3,5 dengan sensitivitas 100% dan spesifisitas 75%. Kesimpulan penelitian ini adalah metode strain ratio setara dengan metode 5-point color scale dalam menilai tumor payudara.
Kata kunci: tumor payudara, strain elastography, strain ratio, 5-point color scale


There are several methods of strain elastography, 5-point color scale is the most commonly used method. 5-point color scale method classifies breast tumor qualitatively and relative subjective with high interobserver variability. So, research on suitability between 5-point color scale method with other methods need to be done. This study asses the suitability between results of strain ratio method and 5-point color scale method on breast tumor. Breast ultrasound using 5-point color scale and strain ratio method was done by researcher, using linear transducer of GE Logic S8 ultrasound machine, then confirmed by consultant breast radiologist. Result of both method was analyzed using ROC curve. There were 28 breast tumor samples in 14 subjects with mean±SD strain ratio was 6.5±1.8 in the tumor with score of 4-5 (malignant) using 5-point color scale method, whereas 2.9±1.7 in tumor with a score of 1-3 (not malignant ) using 5-point color scale method (p 0,000). The area under ROC curve was 0.93±0.05 (p 0,000) for strain ratio value. The best cuttoff point of 3.5 was used for strain ratio, with 100% sensitivity and 75% specificity. In conclusion, result of strain ratio method is equivalent to the 5-point color scale method in assessing breast tumor.
Key words: breast tumor, strain elastography, strain ratio, 5-point color scale