Tesis

Pemantauan dan faktor-faktor yang mempengaruhi kesintasan pasien keganasan ginjal setelah radikal nefrektomi di rumah sakit kanker dharmais = Factors influencing the survival rate of patients with renal cancer post radical nephrectomy at Dharmais Cancer Hospital: Observation from 2009-2016.

Penelitian ini bertujuan untuk mengetahui profil dan faktor-faktor apa saja yang mempengaruhi kesintasan pada pasien-pasien paska radikal nefrektomi di Rumah Sakit Kanker Dharmais. Semua pasien keganasan ginjal paska operasi radikal nefrektomi di Rumah Sakit Kanker Dharmais pada periode Juni 2009- September 2016 diinklusikan, dan data diambil secara retrospektif melalui rekam medis pasien. Variabel yang dinilai dalam studi ini meliputi: jenis kelamin, usia, stadium, histopatologi subyek, tindakan pembedahan, tindakan sistemik setelah tindakan pembedahan, ureum dan kreatinin sebelum dan sesudah operasi, metastasis, pemeriksaan penunjang setelah tindakan pembedahan. Pada penelitian ini, ditemukan bahwa terdapat beberapa faktor yang berhubungan dengan kesintasan, yaitu TNM staging, Fuhrmangrade. Selain itu, pasien yang mendapat kemoterapi setelah tindakan radikal nefrektomi bermakna secara klinis dengan perbedaan lama kesintasan 5 bulan dibandingkan pasien yang tidak mendapatkan kemoterapi.
Kata kunci: Kanker ginjal, radikal nefrektomi, kesintasan


This study aims to determine the profiles and factors that affect the survival rateof post-radical nephrotectomy patients at Dharmais Cancer Hospital. All patients with renal cancertreated with radical nephrectomy surgery at Dharmais Cancer Hospital in the period June 2009-September 2016 were included, and data were retrieved retrospectively through medical record. The variables evaluated in the study consisted of: gender, age, stage, histopathology of the subjects, surgical tretatment, systemic treatment after surgery, urea and creatinine level before and after surgery, metastasis, examinations after surgery. In this study, it was found that there are several factors related to survival, such as: TNM staging and Fuhrman grade. In addition, the patients who received chemotherapy after radical nephrectomy were clinically significant with a 5-month survival difference compared to patients who did not receive chemotherapy.
Keywords: Renal cancer, radical nephrectomy, survival rate