Tesis

Faktor Risiko Tingginya Angka Sindrom Pascakolesistektomi (SPK) di Rumah Sakit dr. Cipto Mangunkusumo pada Tahun 2015 = Risk Factors for High Incidence of Postcholecystectomy Syndrome (PCS) at Cipto Mangunkusumo Hospital on 2015.

Insiden sindrom pascakolesistektomi (SPK) di RS dr.Cipto Mangunkusumo (RSCM) pada tahun 2012 sebesar 54.29%, lebih tinggi daripada penelitian di negara lain. Studi ini bertujuan mencari faktor risiko SPK untuk mengupayakan turunnya insiden SPK.Dilakukan suatu studi cross-sectional terhadap subjek yang menjalani kolesistektomi pada periode Januari - Desember 2015.Total 112 pasien menjalani laparoskopik kolesistektomi.Insiden SPK didapatkan sebesar 45,5%. Pada analisis bivariat didapatkan hubungan signifikan antara SPK dengan lama keluhan praoperasi (p=0,033, OR=2,29), flatulens praoperasi (p=0,000, OR=16,48), gejala non-spesifik praoperasi (p=0,000, OR=6,93), persepsi pasien (p=0,000, OR=5,723). Pada analisis regresi logistik didapatkan flatulens praoperasi (p=0,000, OR=17,152), gejala non-spesifik praoperasi (p=0,012, OR=3,984) dan persepsi pasien praoperasi (p=0,003, OR=5,907) merupakan faktor risiko untuk SPK. Rerata lama observasi pascaoperasi adalah 14,95 bulan. Dari studi ini didapatkan kesimpulan yaitu tingginya angka SPK di RSCM akibat jumlah subjek dengan gejala praoperasi non-spesifik yang lebih tinggi, persepsi praoperasi yang buruk, dan perbedaan lama observasi pascaoperasi.
Kata kunci : sindrom pascakolesistektomi, faktor risiko, kolesistektomi



Incidence of postcholecystectomy syndrome in Cipto Mangunkusumo Hospital at 2012 is 54.29% , higher than ever reported. The objective of the study was to identify risk factors of PCS and decrease its incidence.A cross-sectional study was performed enroll all subjects that underwent cholecystectomy from January to December 2015.All 112 subjects underwent laparoscopic cholecystectomy. We found the incidence for PCS to be 45.5%. Bivariate analysis showed there were significant correlation between PCS and preoperative symptom duration (p=0.033, OR=2.29), preoperative flatulence (p=0.000, OR=16.48), non-specific preoperative symptoms (p=0.000, OR=6.93), poor preoperative perception (p=0.000, OR= 5.723). Multivariate logistic regression analysis showed that only preoperative flatulence (p= 0.000, OR= 17.152), non-specific preoperative symptoms (p= 0.012, OR= 3.984), and poor preoperative perception (p=0.003, OR= 5.907) were independent predictive factors for PCS. Mean of postoperative observation was 14.95 months. Conclusion of this study is high incidence of PCS in RSCM was influenced by larger number of subject with non-specific preoperative symptoms, poor preoperative perception and the difference in duration for postoperative observation.
Keywords:postcholecystectomy syndrome, risk factor, cholecystectomy