Tesis

Korelasi Persentase Lemak Viseral dengan Kekakuan Arteri pada Pasien Lupus Eritematosus Sistemik = Correlation of Visceral Fat Percentage and Arterial Stiffness in Systemic Lupus Erythematosus Patients

Background : Cardiovascular disease is a threat for systemic lupus erythematosus (SLE) patients. Assessment of body mass index (BMI) as the traditional risk factor for cardiovascular disease is not accurate due to the occurrence of rheumatoid cachexia. The measurement of visceral fat percentage is expected to replace the assesment of BMI . Arterial stiffness (AS) is a predictor of cardiovascular disease and many studies have shown arterial stiffness in SLE patients. This study was aimed to find correlation between visceral fat percentage and arterial stiffness in SLE patients. Methods: A cross sectional study was conducted at Cipto Mangunkusumo Hospital rheumatology/allergy-immunology outpatient clinic between March-May 2016. Arterial stiffness was measured by carotid artery ultrasound using rf-echotracking technic to get pulse wave velocity (PWV) value. Assessment of visceral fat percentage was measured by using bioelectrical impedance analysis ( BIA ) - Karada Scan HBF - 214 . Results : 56 SLE female subjects met the inclusion criteria. Mean of PWV 7,23 ± 1,40 m/s, which was categorized in stiff artery. Mean of visceral fat percentage 4,28 ± 2,74%, which was categorized in normal. In bivariate analysis we found no correlation between visceral fat percentage with arterial stiffness (r = 0,101; p = 0,458) Conclusion: There was no correlation between visceral fat percentage with arterial stiffness (PWV) in SLE patients with normal percentage of visceral fat. Keywords: Systemic lupus erythematosus, visceral fat percentage, arterial stiffness, PWV