Tesis

Hubungan Antara Pajanan Kromium Dengan Status Fungsi Hati Pekerja Di Perusahaan Alat Berat PT X Cakung Cilincing = Correlation between Chromium Exposure and Liver Function to worker in Heavy Equipment Manufacturer PT. X Cakung Cilincing

Latar belakang: Pekerja di perusahaan alat berat terutama bagian pengelasan
dapat terpajan berbagai macam logam berbahaya yang terdapat pada plat yang
digunakan. Salah satu logam yang dapat menyebabkan kerusakan sel bahkan
dapat menyebabkan kanker adalah kromium. Hati merupakan salah satu target
organ dan sering mengalami kerusakan akibat logam ini. Tujuan penelitian ini
adalah mencari hubungan kadar kromium di dalam eritrosit dengan status fungsi
hati pekerja.
Metode: Penelitian potong lintang komparasi dilakukan terhadap pekerja yang
terpajan dengan pekerja yang tidak terpajan. Data yang digunakan berdasarkan
hasil pengukuran fisik, hasil pengukuran kromium eritrosit dan Serum Glutamic
Pyruvic Transaminase (SGPT), serta hasil kuisioner.
Hasil: Dari 50 pekerja yang terbagi menjadi 25 orang terpajan dan 25 orang tidak
terpajan, terdapat hubungan bermakna secara statistik antara kadar kromium
eritrosit dengan masa kerja (p=0,044). Tidak terdapat hubungan bermakna secara
statistik antara kadar kromium di dalam eritrosit dengan SGPT (p=0,814).
Kesimpulan: tidak terdapat hubungan bermakna secara statistik mengenai
hubungan kadar kromium dengan kadar SGPT. Namun hasil rerata kadar
kromium pekerja tidak terpajan lebih tinggi daripada populasi normal lainnya.
Kata kunci: kadar kromium eritrosit, SGPT, industri alat berat, pajanan debu kromium


Background: worker in heavy equipment manufacturer especially can be exposed
to a various kinds of harmful metals contained in the plate. One of metal that can
cause cell damage or even cancer which are often used in workplace is chromium.
Liver is one of targeted organ could be damaged due to this metal. The purpose of
this study is to correlate between chromium level in erythrocytes and welder’s
liver function status.
Methods: A Cross Sectional Comparative study was conducted to workers who
were exposed and unexposed. The data used is based on worker’s physical
measurement result, chromium level erythrocytes and Serum Glutamic Pyruvic
Transaminase (SGPT) results, and also questionnaire.
Results: From 50 workers which are consisted of 25 exposed workers and 25
unexposed workers, there is statistically significant correlation between chromium
erythrocytes level and duration of employment (p=0,044). There is no statistically
significant correlation between chromium level in erythrocytes and SGPT
(p=0.814).
Conclusion: There is no statistically significant correlation between erythrocytes
chromium level and SGPT level. But the average result of erythrocytes chromium
level of the unexposed workers were higher compare to other normally
unexposed workers.
Key word: erythrocytes chromium level, SGPT, heavy equipment manufacturer,chromium exposure