Tesis

Perbandingan performa diagnostik sistem skoring International Ovarian Tumor Analysis dengan Risk of Malignancy Index-4 dan indeks morfologi Sassone dalam memprediksi keganasan ovarium prabedah = Comparison of diagnostic performance of scoring system of International Ovarian Tumor Analysis with Risk of Malignancy Index-4 and Sassone morphology index to predict ovarian malignancy preoperatively

Tesis ini membahas perbandingan performa diagnostik sistem skoring International Ovarian Tumor Analysis (IOTA) dengan Risk of Malignancy Index-4 (RMI-4) dan indeks morfologi Sassone dalam memprediksi keganasan ovarium prabedah. Dilakukan uji diagnostik potong-lintang secara retrospektif dengan pasien neoplasma ovarium di RSUPN Dr. Cipto Mangunkusumo dari Januari hingga Desember 2013. Nilai diagnostik dari keempat metode skoring dihitung dengan luaran: sensitivitas, spesifisitas, nilai prediksi positif, nilai prediksi negatif, akurasi dan nilai AUC. Tesis ini menyimpulkan IOTA simple-rules memiliki performa diagnostik lebih baik dibandingkan IOTA subgroup, RMI-4 dan indeks morfologi Sassone.
Kata-kunci: tumor ovarium, kanker ovarium, iota, risk of malignancy, skoring


This thesis compared diagnostic performance of scoring system of International
Ovarian Tumor Analysis (IOTA) with Risk of Malignancy Index-4 (RMI-4) and
Sassone morphology index to predict ovarian malignancy preoperatively. A
retrospective study was done involving subject with ovarian neoplasm at National
General Hospital Dr. Cipto Mangunkusumo on January to December 2013.
Sensitivity, specificity, positive predictive value, negative predictive value,
accuracy and AUC value were calculated. This thesis concluded that diagnostic
performance of IOTA simple-rules were significantly better than IOTA subgroup,
RMI-4 and Sassone morphology index.
Keywords: ovarian neoplasm, iota, risk of malignancy, scoring