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Korelasi antara kadar seng serum dengan kadar superoksida dismutase eritrosit pada penderita HIV/AIDS di RSUPNCM Jakarta = A correlation between concentration of serum zinc and sod levels in hiv/aids patients at RSUPNCM Jakarta.

Prevalensi kasus HIV/AIDS setiap tahun cenderung meningkat sehingga dapat meningkatkan angka kesakitan maupun angka kematian. Penelitian ini merupakan penelitian dengan disain potong lintang yang bertujuan untuk mengetahui korelasi antara kadar seng serum dengan kadar SOD eritrosit pada penderita HIV/AIDS di RSUPNCM Jakarta. Penelitian dilakukan di Kelompok Studi Khusus (Pokdisus) FKUI/RSCM pada akhir bulan Februari 2013 sampai akhir bulan Maret 2013. Pengambilan subyek dilakukan dengan cara consecutive sampling, dan didapatkan 52 orang subyek yang memenuhi kriteria penelitian dari 93 orang subyek yang mengikuti tahap penapisan. Didapatkan subyek (51,9%) berjenis kelamin laki-laki dengan kelompok usia terbanyak 30-39 tahun (65,4%). Status gizi kurang terdapat pada 8 orang (15,4%) dan 44 orang subyek (84,6%) tergolong status gizi cukup. Sebanyak 61,5% limfosit T subyek termasuk kategori II dan 94,2% subyek sudah mendapatkan terapi ARV. Rerata asupan energi subyek sebesar 1850,8±454,6 kkal/hari. Median asupan seng sebesar 6,35 (2,1-14,1) mg/hari. Rerata kadar seng serum 57,69+23,56 µg/dL, hanya 28,8% subyek yang mempunyai kadar seng serum cukup. Kadar SOD eritrosit yang cukup terdapat pada 94,2% subyek dan sisanya sebanyak 5,8% memiliki kadar SOD eritrosit yang rendah. Rerata SOD eritrosit subyek sebesar 1542,10±281,04 U/g Hb. Hasil penelitian ini didapatkan tidak ada korelasi antara kadar seng serum dengan kadar SOD eritrosit penderita HIV/AIDS (r= -0,142, p=0,316).
Kata kunci : seng, SOD, HIV/AIDS


Prevalence of HIV/AIDS tends to increase every year that can caused morbidity and mortality. This research was already done using cross sectional design study to assess correlation between serum Zinc and SOD level in HIV/AIDS patients at RSUPNCM Jakarta. This study was done at Pokdisus FKUI/RSCM from late February until March 2013. Subjects collected by using consecutive sampling method and 52 subjects were matched the study’s criteria over 93 participants. Study shows over half of subjects were male (51.9%) which age mean value is 33.6+4.8 years old and 65.4% at the age 30-39 years old. 15.4% of subjects had poor nutritional status and 84.6% subjects had a good nutritional status. Subjects had 61.5% T lymphocyte belongs to the CDC II category and 94.2% were treated ARV medication. Mean score for energy intake is 1850.8±454.6 kcal/day. Median value of Zinc intake is 6.35 (2.1-14.1) mg/day. Mean score for serum Zinc is 57.69+23.56 µg/dL, only 28.8% subjects had enough serum Zinc status. Mean score for SOD level is 1542.10±281.04 U/g Hb and only 5.8% subjects had a poor SOD level. This research found no correlation between serum Zinc and SOD level in HIV/AIDS patients (r = -0.142, p = 0.316).
Keywords: Zinc, SOD, HIV/AIDS