Skripsi

Perbandingan prevalensi filariasis berdasarkan status lgG4 antifilaria pada penduduk daerah endemis filariasis kelurahan Jati Sampurna dan Jati Karya kecamatan Pondek Gede kabupaten Bekasi Jawa Barat = The comparison of filariasis prevalence based on lgG4 antifilaria status in filariasis endemic population in kelurahan Jati Sampurna and Jati Karya kecamatan Pondok Gede kabupaten Bekasi West Java

Latar Belakang: Filariasis limfatik merupakan penyakit infeksi yang disebabkan oleh cacing nematoda dan ditularkan melalui gigitan nyamuk. Penelitian ini bertujuan untuk membandingkan proporsi filariasis berdasarkan status IgG4 antifilaria antara dua daerah endemis dan mengukur distribusi faktor risiko yang berhubungan signifikan dengan kejadian filariasis pada kedua daerah tersebut. Metode: Penelitian ini menggunakan metode analitik observasional dengan desain studi cross-sectional. Analisis dilakukan terhadap proporsi filariasis berdasarkan status IgG4 antifilaria dan distribusi faktor risiko filariasis pada kedua daerah. Analisis menggunakan uji proporsi kelompok tidak berpasangan Chi-Square. Hasil: Prevalensi filariasis berdasarkan status IgG4 antifilaria pada penduduk kelurahan Jati Karya (73.9%) secara signifikan (p


Background: Lymphatic filariasis is an infectious disease caused by nematode and transmitted by mosquito’s bite. This research aims to compare filariasis proportion based on IgG4 antifilaria status between two endemic areas and to measure filariasis risk factors distribution in these two endemic areas. Method: The method used in this research is observational analitic with cross-sectional design. The number of filariasis based on IgG4 antifilaria in the two regions was then compared, and the distribution of the risk factors of filarial infection affecting the difference of filariasis prevalence between the two regions were analyzed. Data analysis was made using Chi-Square test. Result: Filariasis status based on IgG4 antifilaria in subjects living on kelurahan Jati Karya (73,9%) was significantly (p < 0.001) higher than subjects living on kelurahan Jati Sampurna (53.2%). Analysis of distribution of filariasis risk factors showed that the most important risk factors affecting the difference of IgG4 antifilaria status between the two regions was the demographic profile (p = 0.001), which was divided into indigenous and migrants. Conclusion: Filariasis prevalence based on IgG4 antifilaria status was significantly higher in the residents of kelurahan Jati Karya than in the residents of kelurahan Jati Sampurna. The high prevalence of filariasis in kelurahan Jati Karya was affected by demographic profile, where indigenous people in kelurahan Jati Karya had significantly higher filarial status than those in kelurahan Jati Sampurna. As a result, compared to the residents of kelurahan Jati Sampurna, there was an increase in filariasis exposure to the residents of kelurahan Jati Karya.
Keywords: filariasis, IgG4, antifilaria, demographic profile, economic status, educational status, occupation