Skripsi

Pola Resistensi Bakteri yang Diisolasi dan IRNA RSUPNCM Jakarta lahun 2003 2006. = Bacteri aJ resistance pattern isolated from patients hospitalize:d in RS p, C Jakarta during 2003-2006.

lnfeksi nosokomial adaJah penyebab kematian dan kecac~tan y~mg ulama di seluuh dunia. lnfeksi nosokomifil ban ak disebabkan oleh bakeri muitiresisl n. sehingga I.alalaksana anlihiotik ~ aog baik sangat berpel'an penting. Kepekaan bakleri senantiasa berubahpada waklll dan tempal yaJilg berbeda. schiogga perlu adanyaana j·sis rufll J1IengenaiJ po a resistensi bakteri teltbaap anfbjotik. ujuao penehlian. in" ad" ah untuk mengetahui poln resistensi bakteri yang diisolasi dari IRNA B RSUPNCM selama 4 taboo. Da4a yang di aporkan berasal dari spesimen yang diperilsa di Laboratoriwn Klinik Mikrob~ologi, Depanemen Mikrobiologi FKln dari tahun 2003 sampai 2006. ]so]asi, identifikasi dan kcpekaan bakteri dilakukan sesuai standar pros,edur yang berlaku. Uji kepekaan menggunaan metode difusi cakram sesuai CLSI. Data sekunder yang diambiJ meliputi hasil uji resistensi dari 4 isolat bal1:eri Gram negatif dan 1 Gr-am positif HasiInya mempedihatkan, angka resistensi rata-rata meningkal dati tahun 2003 - 2004 ke 2005 - 2006. Persentase resistensi terlinggi adalab Klebsiella pneumoniae terhadap amoxicilIin yaitu 76.2% pada tahoo 2005 - 2006. Persentase resistensi terendah adalab Escherichia coli terhadap cefepim yaitu 0% pada taboo 2005 - 2006 dan Enterobacter aerogene.;; terhadap cefepim ymtu 0% pacta tab un 2005 - 2006.
Kala Kunci: Infeksi Nosokomial. Antibiotik, pora Resistensi.



NosocomiaJ infecrio is a major cause of mortal it. and disability all 0 er ti e world. osocollial infection i.s prima.ry due to I uhir istance bacleria, th r fore antibiotic treatment management is plaving an important role. Antibiotic resistance·s pattern changes in different time and place', therefore analysis of miorobial resistance pattern should be done routinely. The aim of this study was to e 'amine the bacterial resistance pat1em isolated from IRNA B RSUPN eM against sc:weral antibiotics for 4 years. The data were obtained from specimens examined in the Clinical Microbiology Laboratory, Department 0 Microbiology FacuJty of Medicine University of Indonesia from 2003 - 2006, Isolation identification, and susceptibility test were done according to the standard operational procedure. Disc susceptibility test was done based on CLSJ guideJines. Sec-ondary data were collected from four Gram-negative and one gram positi ve bacterial isolates. The result showed lhat the resistance percentage i creasing from 2003 - 2004 to 2005 - 2006. The hi.ghest resistance percentage was Klebsiella pneumoniae to amoxiciUin, 76.2% in 2005 - 2006. The lowest resistance percentage was Escherichia coli and Enterobanter aerogenes to cefepirn, 0% Ln 2005 - 2006.
Keywords: nosocomial, injection, antimicrobial, resistance.