Skripsi

Prevalensi Hendaya Kognitif dan Hubungannya dengan Kadar Kolesterol Total pada Pasien Usia Lanjut di RSCM. = The Prevalence of Cognitive Impairment and Its Association with Total Cholesterol Level in Elderly Patient in RSCM.

Populasi penduduk usia lanjut di Indonesia semakin meningkat. Hendaya kognitif merupakan salah satu manifestasi dari proses degeneratif yang dapat menyebabkan terganggunya aktivitas sehari-hari, serta menjadi beban ekonomi dan sosial. Kadar kolesterol total diduga memiliki hubungan dengan hendaya kognitif. Penelitian ini merupakan penelitian analitik dengan desain potong lintang. Sampel merupakan pasien usia lanjut ( ≥ 60 tahun) yang berobat ke poliklinik geriatri terpadu RSCM. Hendaya kognitif didefinisikan dengan nilai MMSE < 24 dan kadar kolesterol total dilihat dari pemeriksaan laboratorium. Didapatkan prevalensi hendaya kognitif sebesar 22,1%. Setelah dilakukan penyesuaian terhadap faktor perancu (hipertensi, stroke, diabetes mellitus) menggunakan regresi logistik, didapatkan bahwa kolesterol total tidak berhubungan dengan hendaya kognitif (adjusted OR 0,85; IK 95% 0,40 sampai 1,79; p 0,672). Perbedaan hasil dengan penelitian-penelitian terdahulu dapat disebabkan oleh perbedaan desain dan jumlah sampel penelitian.
Kata kunci: Usia lanjut, hendaya kognitif, kolesterol total.



The population of elderly in Indonesia is increasing. Cognitive impairment is one of degenerative process’ manifestation that causes activity daily living disturbance and leads to economic and social burden. Several previous studies found relation between total cholesterol and cognitive impairment. This is an analytic cross sectional study. The subject is elderly patient ( ≥ 60 years old) that have medical treatment in integrated geriatric clinic RSCM. The subject was diagnosed having cognitive impairment if the MMSE score is < 24. Total cholesterol level was seen from the laboratory examination result. The result shows that the prevalence of cognitive impairment is 22,1%. After adjustment of confounding factors (hypertension, stroke, diabetes mellitus) with logistic regression, it was found that total cholesterol was not associated with cognitive impairment (adjusted OR 0.85, 95% CI 0.40 to 1.79, p 0.672). The different result between this study and previous studies might be caused by the difference in design and number of sample. Key words: Elderly, cognitive impairment, total cholesterol.